TRIMIX & E.D.
TRIMIX & E.D.
The word “Trimix” became a well-known term for a large number of male patients with erectile dysfunction (E.D.) I want to clarify the meanings of this term and confusion it creates apparently both among patients and some health care practitioners.
Let’s talk semantics: “tri” stands for three and “mix” is mix. This is very simple, right? Tri-mix is a mix of three elements, no matter what they are.
If we check Wikipedia, we’ll see that “Trimix may refer to:
· Trimix (injection), an injection containing alprostadil, papaverine, and phentolamine, used to treat erectile dysfunction”
Obviously in our discussion we refer to the second version on Wikipedia as I already connected the term “Trimix” to E.D. Your online search will take you to different sites that will give you a lot of detailed information about what Trimix is, what it contains, how can you use it, etc. And probably the more you read, the more you’ll get confused.
Why am I saying this? This is because one can easily notice the variation of the three ingredients in “Trimix” compositions. Furthermore, there is even more variety in the strengths of the three chemicals that make the composition of the “Trimix”, and you may wonder why.
The answer is a little more complex: “Trimix” is not a manufactured (made by a pharmaceutical company) product. While all three ingredients in “Trimix, no matter what they are, are FDA approved separate products, “Trimix” has to be made by a compounding pharmacy based on a doctor’s prescription. Because the name became so popular among E.D. sufferers and among Urologists who mainly prescribe it, some patients and even some practitioners are led to believe that there is only one “Trimix” and only one maker of it.
There is a compounding pharmacy that has even trade marked the name “Trimix” for urethral gel administration we want to be clear that in this article I am referring to Trimix injection.
Compounding means customizing a medicine based on a patient’s unique needs. Your doctor will write the combination and the strengths that work in your case, and it has to be a close collaboration between you, your doctor and your compounding pharmacist to adjust your medication for the best outcome.
The most commonly combined three ingredients are the ones mentioned above in Wikipedia quote:
Alprostadil strength between: 10-25 mcg/ml
Papaverine strength between: 18-25 mg/ml
Phentolamine strength between: 1-2 mg/ml
Some doctors prescribe “Bi-mix” or “Quad-mix” in various strength and ingredient combinations and the amount injected also varies from one patient to another or even from one time to another for the same patient. I want to leave you with one clear understanding: it is very important for you to collaborate with your doctor and your compounding pharmacist to find the most appropriate option that works for you.
For June, HM Compounding is featuring a special on TriMix injections for Mens Health Month. $79.99 for any strength of “TriMix”, up to a 10ml vial plus Free Shipping in the Tri-State area.

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